About

manuel-corpas-web

 

Dr. Corpas is an experienced community builder and scientific communications strategist in Genomics and Computational Biology. Currently based in Cambridge, UK, he is the Scientific Lead at Repositive, a genome data sharing platform company. Before Repositive, Corpas was a 2016 fellow of the Software Sustainability Institute and Project Leader at The Genome Analysis Centre (now Earlham Institute, Norwich, UK). There he was Technical Coordinator of the Bioinformatics Research Infrastructure ELIXIR-UK, coordinator of the BioJS open source community and Chair of the Technical Committee for the Global Organisation for Bioinformatics Learning, Education and Training (GOBLET). While doing he graduate studies he became Founder and Inaugural Chair for the International Society for Computational Biology (ISCB) Student Council (2004), the leading student body in Computational Biology. Later in his career, he was elected ISCB Board of Directors (2013-2016). He holds a Ph.D. in Computer Science from the University of Manchester, UK, and did his postdoctoral work in clinical genomics at the Wellcome Trust Sanger Institute, Cambridge, developing the DECIPHER database, a widely-used clinical interpretation resource for patients with rare genomic disorders. Dr. Corpas is a prolific author and speaker, with circa 50 authored scientific publications and the acclaimed ‘Perfect DNA’ book; a speculative futuristic novel exploring the ethical and social implications of personal genetic testing in society. His blog https://personalgenomics.zone/ is followed by ~3,000 subscribers and serves The Precision Medicine Podcast, a podcast about current technological and ethical advancements and challenges in Precision Medicine.

 

Education

2002-2007 PhD Bioinformatics, University of Manchester, UK

2000-2002 MSc Computational Molecular Biology, University of Manchester, UK

1999-2000 Erasmus program, University of Southampton, UK

1995-1999 BSc (Hons) Biomedical Sciences, University of Navarre, Spain

Positions Held   

  • Sep 2016 – Present Repositive.io, Cambridge, UK (Scientific Lead). My goals revolve around: a) building a community of engaged users of Repositive products b) building successful use cases and applications that use human genome datasets and c) raising Repositive’s scientific profile around the theme of human genomics data sharing.
  • Feb 2012 – Sep 2016 The Genome Analysis Centre (TGAC), Norwich, UK (Project Leader). Next Generation Sequencing data analysis, expression and regulation mechanisms of various organisms, including human health. Development of visualisation methods for -Omics Big Data. Development of tools for analysis of personal genomes.
  • Sep 2014 – Feb 2016 Technical Coordinator, ELIXIR-UK. Coordinate implementation of Big Data infrastructure to support the establishment of sustainable bioinformatics resources Europe-wide.
  • Apr 2011 – Jan 2015 itico.org. Director of Itico, a non-for-profit organisation registered in Cambridge, England. Development of the iAnn platform, recently adopted by ELIXIR and GOBLET (Global Organisation for Bioinformatics Learning, Education and Training).
  • Sept 2008 – Jan 2012 Wellcome Trust Sanger Institute, Cambridge, UK (Senior Web Developer/Postdoctoral Scientist; Lead Scientist: Dr Nigel Carter, Lead Clinician: Dr Helen Firth). Research and development of DECIPHER (http://decipher.sanger.ac.uk), a clinical genomics database for diagnosis of patients with rare genomic disorders. Developed bioinformatics tools for visualisation and analysis of personal genomes.
  • Jan-Aug 2008 European Bioinformatics Institute, UK (Scientific Programmer; supervisors: Dr Pascal Kahlem and Dr Ewan Birney). Set up a systems biology database, EnDICTION, for integration of computer-generated protein-protein interactions predictions from the ENFIN network of Excellence.
  • Aug-Dec 2007 Spanish National Bioinformatics Institute, Spain (Scientific Coordinator for the institute, led by Alfonso Valencia). Developed the Institute’s portal and delivered strategic training of Spanish bioinformatics tools throughout the country.
  • Jul-Sep 2003 San Diego Supercomputer Center, University of California at San Diego, USA (Internship at the Protein Data Bank in Phil Bourne’s group). Studied the relationship of structural homology vs. sequence homology using PDB and PRINTS databases data. Funded by the World Universities Network.
  • Apr 2002 – Jun 2007 Faculty of Life Sciences and Faculty of Computer Science, University of Manchester, UK (PhD Student; supervisors: Prof Terri Attwood and Dr Steve Pettifer). Study of structural factors contributing most to sequence conservation in protein families. Created web tools that identify conserved protein sequence motifs. Funded by the Department of Computer Science at the University of Manchester.
  • Jul-Oct 2001 Virginia Bioinformatics Institute (Internship for MSc Dissertation; Supervisor, Prof Pedro Mendes). Parser in C++ for GEPASI (a biochemical pathway simulator) to allow automatic exchange of data with Systems Biology Markup Language (SBML),